Every year, three friends take a vacation away from their wives. This year, henpecked Phil (Daniel Stern), newly married Ed (Bruno Kirby), and Mitch (Billy Crystal) — terrified of his midlife crisis — decide to reignite their masculinity by taking a supervised cattle drive across the Southwest. Under the supervision of gruff cowboy Curly (Jack Palance), the men set out on a journey that turns unexpectedly dangerous. The three men bond along the way to conquering their fear of aging.